The importance of set and setting

A blog post exploring the importance of set and setting to a psilocybin trip

Drew Donaldson

4/4/20252 min read

Advice on the set and setting for a therapeutic psilocybin journey
Advice on the set and setting for a therapeutic psilocybin journey

The Importance of Set and Setting

Psilocybin is gaining recognition as a promising tool for mental health care and self-exploration. Clinical trials and personal reports alike point to its ability to foster profound healing, insights, and emotional breakthroughs. But the difference between a transformative experience and a difficult one often comes down to two simple concepts: set and setting.

What Do “Set and Setting” Mean?

'Set and setting' have become familiar buzzwords in the psychedelic community. The terms were popularised in the 1960s by psychedelic researcher Timothy Leary, but they remain just as relevant today. Generally, they are defined in the following ways:

  • Set (Mindset): Your inner state before and during the experience—your mood, expectations, fears, hopes, and intentions.

  • Setting: The external environment—the physical space you’re in, the people around you, and the overall atmosphere.

Together, these two factors shape the direction, depth, and safety of a psilocybin journey.

Why Set Matters

Psilocybin amplifies what’s already present in the mind. Entering the experience with unresolved stress, fear, or chaotic thoughts can heighten anxiety and make the trip overwhelming. On the other hand, approaching the session with openness, curiosity, and trust can lead to deeper insights and healing.

Preparing Your Set

Using our pre-flight guided meditation will help you prepare for success. Utilising alpha wave binaural beats (associated with states of relaxed meditation) and a soft, guided narration, it will help you:

  • Clarify your intention: What do you hope to achieve from your journey?

  • Prepare yourself emotionally: Addressing immediate stressors before you take flight.

  • Ground yourself: Using meditation and breathwork to cultivate a sense of calm.

Why Setting Matters

The environment acts as a container for the journey. A noisy, chaotic, or unsafe space can trigger unease or paranoia. In contrast, a safe and supportive setting allows you to relax, surrender, and explore inner landscapes without fear. The simple act of tidying and cleaning your space can make a big difference to the outcome of your journey. Open some windows. Light a candle. Tend to these small details and you will reap the benefits later. Before your journey, consider the following:

  • Physical space: Is it comfortable, quiet and clean? Soft lighting and music can help set the tone. (Our Ascent Phase audio is ideal!)

  • Safety: Will you have a sitter nearby? A trusted friend or professional is a great source of reassurance.

  • Nature connection: Can you see a tree from your window, or open a door to your garden? Many find that being in or near nature deepens feelings of peace. If you're in the middle of a city or town, consider choosing music with natural sounds or themes.

Integrating the Experience

Set and setting don’t end when the psilocybin wears off. The integration process—reflecting on and applying insights—is part of the broader container. Journaling, therapy, or community support can help translate profound moments into lasting change. Our deep integration audio will guide you through this process.

Closing Thoughts

Psilocybin is not just about the substance itself; it’s about the portal it opens - a window into your inner world and emotions. The right mindset and environment can turn the experience into a powerful therapeutic tool. Without attention to set and setting, however, even a well-intended trip can feel destabilising. With them, the potential for healing and growth expands dramatically.

Approach with care, intention, and respect—and psilocybin may offer not just visions, but true transformation. We wish you success on your travels. ❤️